Archives: Studies

Goal: To learn more about the relationship between oxidative stress levels (from our diet, environmental toxins, and normal metabolic processes) in both parents and how this could affect embryo and pregnancy health. Who is Eligible? Process Step 1: Enrollment If you think you are eligible and want to participate, speak with your primary doctor. You…

Why is this study being done? The objective of the study is to provide evidence for the safety and effectiveness of the May Health System in transvaginal ablation of ovarian tissue under transvaginal ultrasound guidance to restore ovulation in women with infertility due to polycystic ovary syndrome (PCOS) who have not responded to first-line ovulation…

Multi-center, parallel group, randomized controlled trial of modified natural versus programmed cycles for frozen embryo transfer and their association with preeclampsia and live births The NatPro study team is currently seeking patients to participate in a fertility research study designed to compare two protocols commonly used for frozen embryo transfer. The two protocols are called modified natural cycle and…

The REST-UP Study is about restoring metabolic and reproductive health with sleep in individuals with Polycystic Ovary Syndrome. This study specifically aims to investigate why some people with obstructive sleep apnea have higher levels of insulin resistance. Study investigators will also examine the role of hypoxia (low levels of oxygen in the blood at night)…

Our goal with the HOPE project is to Harness multiple Opportunities for Pregnancy loss Exploration.In the United States, millions of women get pregnant and have successful pregnancies every year. Unfortunately, miscarriage also occurs in 8-20% of clinically recognized pregnancies. Many miscarriages can occur due to large chromosomal abnormalities. These abnormalities can be recognized and mitigated with the increasing use…

One of the most common fertility treatments is intrauterine insemination (IUI). Sperm is typically prepared for IUI with density gradient centrifugation, though this technique can damage the genetic material in sperm.  Studies of sperm prepared with a newer process using the FDA-approved Zymot Multi sperm preparation device have shown a 67% higher pregnancy rate (an…

There has been a lack of literature describing both short and long-term adverse consequences of egg donation. This study hopes to 1) characterize the medical, emotional, and psychosocial impact of oocyte donation following donation, 2) to describe one’s subjective experience with the process, 3) to assess the potential impact this decision had on one’s own medical…

Women have variable amounts of estrogen produced from the growing follicles that circulates in their blood as they undergo ovarian stimulation. Higher studies suggest this difference may be related to how women metabolize estrogen. This matters because it effects how much hormone goes in circulation and may have implications on how effective medications are, as…

The purpose of this study is to explore the relationship between genetic and environmental factors that may explain PCOS. We will use information collected during visits to our PCOS clinic and the family history of PCOS patients to learn about the causes and effects of PCOS. You may be eligible if you are: female (or assigned…

This study is evaluating the effects of specific diets on the regulation of menstrual cycles in PCOS patients to help improve fertility treatments for women with PCOS. Participants will follow a paleolithic-type diet or a health ADA-recommended diet to see if either one can help regulate menstrual cycles. Participation will be supported by visits with…