One of the most common fertility treatments is intrauterine insemination (IUI). Sperm is typically prepared for IUI with density gradient centrifugation, though this technique can damage the genetic material in sperm. Studies of sperm prepared with a newer process using the FDA-approved Zymot Multi sperm preparation device have shown a 67% higher pregnancy rate (an increase from 9% to 15%), less DNA damage, higher sperm motility (movement/speed), and better morphology (shape).
The purpose of this randomized controlled trial is to figure out which sperm preparation yields a higher pregnancy rate – density gradient centrifugation compared to the Zymot Multi sperm preparation device.
You may be eligible if you are: planning your first intrauterine insemination cycle and are not using a frozen sperm source
