ROAR Study Reactive Oxygen species And Reproduction ROAR Reactive Oxygen species And Reproduction

Goal: To learn more about the relationship between oxidative stress levels (from our diet, environmental toxins, and normal metabolic processes) in both parents and how this could affect embryo and pregnancy health.

Who is Eligible?

  • Females aged 18-43 starting an IVF cycle
  • Planning to do genetic testing (PGT-A)
  • Planning to freeze all embryos (no fresh transfer)
  • Partner must be available to provide a fresh sperm sample on the day of retrieval

Process

Step 1: Enrollment

If you think you are eligible and want to participate, speak with your primary doctor. You may also be contacted by one of the UCSF Fellows

Step 2:

Go through your IVF cycle as planned. There will be a blood draw for both partners on the day of the egg retrieval

Step 3: Retrieval

We will collect follicular fluid (which is normally discarded) to test for oxidative stress levels within the ovary

Compensation

If you do not have insurance coverage for pre-implantation genetic testing for aneuploidy (PGT-A), the cost of the PGT-A testing will be covered by the study and will be offered free of charge!

Email us at roar@ucsf.edu

Mitchell Rosen, MD
Principal Investigator
Kaia Schwartz
Principal Investigator
Nikolaus Lenhart
Research Coordinator
Violet Marko
Research Coordinator